Berberine Benefits

Balance your blood sugar. Balance your weight. Balance your gut.

Berberine has been used for a long time in Ayurveda and Ancient Chinese Medicine traditions, and is a heavily-researched ingredient. As of 2019, there were 77 clinical studies evaluating its efficacy! 

Here's what it does best: 

Blood Sugar Regulation

  • In a study involving 80 adults, those who took 1.2 grams of berberine daily for a month showed support for normal fasting and after-meal blood glucose levels compared to a placebo group receiving usual care. [1]

  • Another study with 136 females with PCOS found that 1 gram of berberine per day supported normal fasting blood glucose levels when compared to medications and another dietary supplement. [2]

  • A meta-analysis of 47 clinical trials confirmed that berberine supplementation helps maintain healthy blood glucose levels. [3]

Weight Management

    • The same study with 136 females with PCOS revealed that 1 gram of berberine per day supported healthy weight compared to medications and another dietary supplement. [2]

    • The meta-analysis mentioned earlier showed that berberine supplementation, when taken for at least 8 weeks, supports healthy weight. [3]

    Gastrointestinal Microbial Balance

    • Experimental studies have demonstrated that berberine enriches populations of gut microbes producing butyrate, a short-chain fatty acid known to support gut barrier function. [4] [5]
    1. Cao and Su. Experimental and Therapeutic Medicine. 2019;17(4):3009-3014.
    2. Mishrea, Verma and Jaduan. Cureus. 2022;14(1):e21781. PMID: 35251841
    3. Zamani et al. Frontiers in Nutrition. 2022;9:1013055. PMID: 36313096
    4. Wang et al. Metabolism. 2017;70:72-84. PMID: 28403947 
    5. Sun et al. Obe Facts. 2017;9(6):365-378. PMID: 27898425
    6. Guilloteau. Nutr Res Rev. 2010;23(2):366-84. PMID: 2093716

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